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Fhir

MCP Server that connects AI agents to FHIR servers. One example use case is querying patient history in natural language.

biology-medicine-and-bioinformaticsaiagent
By the-momentum
9117Updated 8 months agoPythonMIT

Installation

npx -y fhir-mcp-server

Configuration

{
  "mcpServers": {
    "fhir-mcp-server": {
      "command": "npx",
      "args": ["-y", "fhir-mcp-server"]
    }
  }
}

How to use

  1. Run the installation command above (if needed)
  2. Open your Claude Code settings file (~/.claude/settings.json)
  3. Add the configuration to the mcpServers section
  4. Restart Claude Code to apply changes

<a name="readme-top"></a>

<div align="center"> <img src="https://cdn.prod.website-files.com/66a1237564b8afdc9767dd3d/66df7b326efdddf8c1af9dbb_Momentum%20Logo.svg" height="80"> <h1>FHIR MCP Server</h1> <p><strong>Model Context Protocol (MCP) Server for Fast Healthcare Interoperability Resources (FHIR)</strong></p>

Contact us Visit Momentum MIT License

</div>

πŸ“‹ Table of Contents

πŸ” About The Project

FHIR MCP Server implements a complete Model Context Protocol (MCP) server, designed to facilitate seamless interaction between LLM-based agents and a FHIR-compliant backend. It provides a standardized interface that enables full CRUD operations on FHIR resources through a comprehensive suite of tools - accessible from MCP-compatible clients such as Claude Desktop, allowing users to query and manipulate clinical data using natural-language prompts.

✨ Key Features

  • πŸš€ FastMCP Framework: Built on FastMCP for high-performance MCP server capabilities
  • πŸ₯ FHIR Resource Management: Full CRUD operations for all major FHIR resources
  • πŸ“„ Intelligent Document Processing: AI-powered document ingestion and chunking for multiple formats including TXT, CSV, JSON, and PDF
  • πŸ” Semantic Search: Advanced document search using vector embeddings (via Pinecone)
  • 🧠 RAG-Ready: Retrieval-Augmented Generation pipeline with context-aware document queries
  • πŸ” Secure Authentication: OAuth2 token management for FHIR API integration
  • πŸ“Š LOINC Integration: Standardized medical terminology lookup and validation
  • 🐳 Container Ready: Docker support for easy deployment and scaling
  • πŸ”§ Configurable: Extensive .env-based configuration options

πŸ—οΈ Architecture

The server is built with a modular architecture:

  • MCP Tools: Dedicated tools for selected FHIR resource types, with others handled by a generic tool
  • Fhir Server Client: Handles FHIR API communication and authentication (OAuth2 and more planned)
  • RAG Services: Embedding-based document processing and semantic retrieval
  • Vector Store: Pinecone integration for similarity-based search
  • LOINC Client: Integration with LOINC API for terminology resolution and validation
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πŸ’‘ Demo

This demo shows how Claude uses the fhir-mcp-server to communicate with a FHIR server (in this case Medplum) to answer questions. You will see, among other things:

  • utilization of the request_patient_resource tool which retrieves basic patient information
  • utilization of the request_condition_resource tool to answer the question whether any of the previously diagnosed diseases may cause symptoms that the patient is currently complaining about
  • utilization of the request_medication_resource, request_encounter_resource, request_generic_resource tools to answer the question whether the patient has already received any treatment for hypertension

You can observe how Claude automatically selects the tools worth using to answer the question based on the user's query.

https://github.com/user-attachments/assets/3a3a8ed3-f881-447d-af03-5f24432a2cdd

<details> <summary>Lab History Analysis</summary>

Here you can observe how Claude first uses the tool searching for LOINC codes for the lipid panel specific codes, but not finding any related observations in FHIR server, it repeats the search for individual biomarkers that make up such a panel.

https://github.com/user-attachments/assets/2fb39801-d5d6-4461-bedd-9f58ab4d52ec

</details> <details> <summary>FHIR Synthetic Data Generator</summary>

Developers working with FHIR often need to generate specific test data to validate FHIR server functionality, such as search capabilities and data relationships. While you can use Synthea to generate synthetic data and then manually import the resulting bundles to your server, fhir-mcp-server streamlines this process by allowing you to generate and deploy test data directly through Claude.

This eliminates the typical workflow of running synthea separately, downloading bundles, and manually importing them to your FHIR server. Instead, you can create targeted test scenarios, generate appropriate synthetic data, and populate your server all within Claude's interface.

https://github.com/user-attachments/assets/d87da1d8-6401-4a9e-a6f0-50ba23396e12

Note: fhir-mcp-server was not designed with this use case in mind, so as you'll see in the demo, it doesn't work perfectly - what can be observed, however, is how well the LLM handles using trial and error to correct any wrong choices.

</details>

πŸš€ Getting Started

Follow these steps to set up FHIR MCP Server in your environment.

Prerequisites

  • Docker (recommended) or uv: For dependency management

    πŸ‘‰ uv Installation Guide

  • FHIR Server Account: Access to FHIR API (e.g. Medplum)

  • Pinecone API key (required for document search): Enables vector-based search over processed documents. Without it, semantic retrieval features will be unavailable.

    πŸ‘‰ Create Pinecone Account

  • LOINC Account (optional): Enables retrieval of the latest LOINC codes from the official API. Without it, the system relies on static or language model-inferred codes, which may be outdated or imprecise.

    πŸ‘‰Create LOINC Account

Installation & Setup

  1. Clone the repository:

    git clone https://github.com/the-momentum/fhir-mcp-server
    cd fhir-mcp-server
  2. Set up environment variables:

    cp config/.env.example config/.env

    Edit the config/.env file with your credentials and configuration. See Environment Variables

  3. Install Dependencies

    For Docker-based execution run:

    make build

    For uv-based execution run:

    make uv
  4. Update the MCP Client configuration

    e.g. Claude Desktop -> edit claude_desktop_config.json

  • Docker

    {
       "mcpServers": {
          "docker-mcp-server": {
             "command": "docker",
             "args": [
                "run",
                "-i",
                "--rm",
                "--init",
                "--name",
                "fhir-mcp-server",
                "--mount", // optional - volume for reload
                "type=bind,source=<your-project-path>/app,target=/root_project/app", // optional - volume for reload
                "--mount",
                "type=bind,source=<your-project-path>/config/.env,target=/root_project/config/.env",
                "-e", "TRANSPORT_MODE=stdio", // Set transport mode: stdio, http, or https
                "mcp-server:latest"
             ]
          }
       }
    }

    Make sure to replace <your-project-path> with the actual path to your installation

  • uv

    Firstly, get uv path from terminal:

    • Windows:

      (Get-Command uv).Path
    • MacOS/Linux:

      which uv

    Then, update config file:

    {
       "mcpServers": {
          "uv-mcp-server": {
             "command": "uv",
             "args": [
                "run",
                "--frozen",
                "--directory",
                "<your-project-path>",
                "start"
             ],
             "env": {
             "PATH": "<uv-bin-folder-path>"
             }
          }
       }
    }

    Make sure to replace <uv-bin-folder-path> with the actual uv path (to bin folder)

  1. Restart MCP Client

    After completing all of the above steps, restart the MCP Client to apply the changes. In some cases, you may need to terminate all related processes using Task Manager or your system's process manager. This ensures that:

    • The updated configuration is properly loaded
    • Environment variables are correctly applied
    • The FHIR MCP client initializes with the correct settings
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πŸ”§ Configuration

πŸ” Security & Encryption

The FHIR MCP Server includes built-in encryption infrastructure to protect sensitive configuration values. Sensitive fields like API keys and passwords are automatically encrypted and decrypted at runtime.

You are allowed to store passwords as a plain text, but if you want to have them encrypted, follow the instruction below.

Setting Up Encryption

<details> <summary>Automated Setup (Recommended)</summary>

For most users, use the automated setup script:

# uv method
uv run scripts/cryptography/setup_encryption.py

# docker method
docker exec fhir-mcp-server uv run scripts/cryptography/setup_encryption.py

This script will:

  1. Check for MASTER_KEY in config/.env and generate one if needed
  2. Automatically encrypt all sensitive values (LOINC_PASSWORD, FHIR_SERVER_CLIENT_SECRET, PINECONE_API_KEY)
  3. Update your .env file with encrypted values
  4. Skip empty variables and already encrypted values
</details> <details> <summary>Manual Setup</summary>
  1. Generate a Master Key:

    # uv method
    uv run scripts/cryptography/generate_master_key.py
    
    # docker method
    docker exec fhir-mcp-server uv run scripts/cryptography/generate_master_key.py

    Put that key as a MASTER_KEY environment variable in .env.

  2. Encrypt Sensitive Values:

    # uv method
    uv run scripts/cryptography/encrypt_setting.py "your_secret_value"
    
     # docker method
    docker exec fhir-mcp-server uv run scripts/cryptography/encrypt_setting.py "your_secret_value"
  3. Decrypt Values (for verification):

    # uv method
    uv run scripts/cryptography/decrypt_setting.py "encrypted_value"
    
     # docker method
    docker exec fhir-mcp-server uv run scripts/cryptography/decrypt_setting.py "encrypted_value"
</details>

Encrypted Configuration Fields

The following fields are automatically encrypted when using EncryptedField:

  • FHIR_SERVER_CLIENT_SECRET - OAuth2 client secret for FHIR server
  • LOINC_PASSWORD - LOINC account password
  • PINECONE_API_KEY - Pinecone API key for vector search

Environment Variables

VariableDescriptionExample ValueEncryption
MASTER_KEYMaster encryption keygAAAAABl...Required
FHIR_SERVER_HOSTFHIR API host URLhttps://api.medplum.comNo
FHIR_BASE_URLFHIR base path/fhir/R4No
FHIR_SERVER_CLIENT_IDOAuth2 client ID for FHIR019720e7...No
FHIR_SERVER_CLIENT_SECRETOAuth2 client secret for FHIRgAAAAABl...Yes
LOINC_ENDPOINTLOINC API search endpointhttps://loinc.regenstrief.org/searchapi/loincsNo
LOINC_USERNAMELOINC account usernameloinc-userNo
LOINC_PASSWORDLOINC account passwordgAAAAABl...Yes
PINECONE_API_KEYPinecone API keygAAAAABl...Yes
EMBEDDING_MODELHugging Face embedding model nameNeuML/pubmedbert-base-embeddingsNo
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πŸ› οΈ MCP Tools

The FHI

…

View source on GitHub